Table 1

The effect of pirfenidone on the transcription of TGF-β and 18S rRNA at 14 days after BL instillation

ProbesDensitometry Reading
BL + CDBL + PD
TGF-β620  ± 132416  ± 881-150
18S rRNA1412  ± 3911502  ± 372

The nuclear run-off experiment was carried out as described inMaterials and Methods. Each value represents mean ± S.E. of five animals in duplicate experiments.

  • 1-150T test indicated that BL + PD treatment group was significantly lower (P ≤ .05) than that of BL + CD group.