Study | Liver weight | CIn | Biliary Output | Hepatic Venous Output | Total Metabolism | Recovery | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% of input rate | % of total bile | % of input rate | % of perfusate | % of input rate | % of total metabolism | % of input rate | |||||||||||
EA-SG | EA-CG | EA-CYS | EA-NAC | EA | EA | EA-SG | EA-SG | EA-CG | EA-CYS | EA-NAC | |||||||
g | μM | ||||||||||||||||
1 | 9.2 | 8 | 78 | 88.3 | 11.7 | 0.0 | 0.0 | 0.0 | 35 | 92.0 | 8.0 | 80.2 | 88.7 | 11.3 | 0.0 | 0.0 | 112 |
2 | 13.6 | 12 | 75 | 97.0 | 3.0 | 0.0 | 0.0 | 0.0 | 27 | 93.8 | 6.2 | 76.7 | 97.1 | 2.9 | 0.0 | 0.0 | 102 |
3 | 12.0 | 15 | 70 | 92.0 | 8.0 | 0.0 | 0.0 | 0.0 | 35 | 82.1 | 17.9 | 76.1 | 92.7 | 7.3 | 0.0 | 0.0 | 105 |
4 | 8.4 | 28 | 44 | 93.0 | 6.7 | 0.0 | 0.3 | 0.0 | 56 | 79.4 | 20.6 | 55.5 | 94.5 | 5.3 | 0.0 | 0.2 | 100 |
5 | 9.6 | 49 | 53 | 94.7 | 5.0 | 0.1 | 0.1 | 0.0 | 60 | 91.5 | 8.5 | 58.4 | 95.2 | 4.6 | 0.1 | 0.1 | 113 |
6 | 10.2 | 93 | 30 | 94.9 | 3.0 | 0.4 | 0.6 | 1.1 | 72 | 94.3 | 5.7 | 33.5 | 96.5 | 2.7 | 0.4 | 0.5 | 102 |
7 | 11.4 | 112 | 19 | 99.2 | 0.6 | 0.0 | 0.0 | 0.2 | 81 | 95.9 | 4.1 | 22.4 | 99.5 | 0.5 | 0.0 | 0.0 | 100 |
8 | 8.6 | 152 | 14 | 96.5 | 1.7 | 0.6 | 0.5 | 0.7 | 73 | 97.5 | 2.5 | 15.4 | 97.6 | 1.5 | 0.6 | 0.4 | 87 |
9 | 11.0 | 153 | 16 | 98.5 | 1.3 | 0.0 | 0.2 | 0.0 | 84 | 95.9 | 4.1 | 19.1 | 98.7 | 1.1 | 0.0 | 0.2 | 100 |
10 | 8.2 | 194 | 14 | 94.1 | 4.7 | 0.8 | 0.1 | 0.3 | 75 | 96.5 | 3.4 | 16.5 | 95.3 | 4.0 | 0.6 | 0.1 | 89 |
Mean | 10.2 | 94.8 | 4.6 | 0.2 | 0.2 | 0.2 | 91.9 | 8.1 | 95.6 | 4.1 | 0.2 | 0.2 | 101 | ||||
S.D. | 1.7 | 3.1 | 3.3 | 0.3 | 0.2 | 0.4 | 5.9 | 5.9 | 3.0 | 3.1 | 0.2 | 0.2 | 8 |