P values and IC50 values of non-aliphatic organic cations
| Compound | MW of Organic Cations | P (octanol/water) | Log(P) | IC50 |
|---|---|---|---|---|
| μM | ||||
| Procainamide | 235 | 0.009 | −2.045 | 107 ± 46 |
| Vecuronium | 558 | 0.1652-a | −0.782 | 237 ± 8 |
| Quinine | 324 | 2.32 | 0.365 | 22.6 ± 5.5 |
| Quinidine | 324 | 2.45 | 0.389 | 23.4 ± 6.4 |
IC50 values were obtained by fitting data from two to four separate experiments as described in Experimental Procedures and are presented as means ± S.D.
↵2-a P values cited from Proost et al. (1997).