Table 1

Potencies of clozapine and olanzapine as inhibitors of [125I]Iodoproxyfan binding in various mouse brain regions

RegionKi Values (μM)
ClozapineOlanzapine
Cerebral cortex2.2  ± 0.422  ± 6
Striatum1.2  ± 0.236  ± 5
Hypothalamus3.1  ± 0.872  ± 6