Table 1

Characterization of noninduced Caco-2, MDR-1-transfected Caco-2, as well as vinblastine-induced Caco-2 cells with respect to expression of P-gp

	Maximum Binding Capacity		Mean Factor of Increase in Binding Capacity
	fmol/1 × 10⁶cells
Non-induced Caco-2	631 /721	n = 2, individual results
MDR-1 transfected	963 /1060	n = 2, individual results	1.5
Induced Caco-2	1660 ± 671	n = 6, mean ± S.D.	2.5

Maximum binding capacity of cell preparations determined by saturation experiments with RBA using [³H]verapamil as the radioligand and mean factor of increase in binding capacity of radioligand to P-gp for transfected and induced cells (noninduced = 1).