Table 1

Immunoquantification of the levels of CYP2B6 and nirvanol formation in a bank of 19 human liver microsomal specimens

Human Liver CodeImmunoquantified CYP2B6 (Relative to HL-A)Nirvanol Formation (pmol/min/mg Protein)1-a
A100.01-b 6.0
B81.81.8
C79.03.6
D230.16.0
E508.924.7
F28.56.7
G183.24.9
H39.22.4
I387.019.3
J91.46.4
K60.23.3
L23.82.4
M116.64.9
N78.23.3
O2543.647.6
P1512.329.3
Q148.58.4
R127.05.1
S287.413.6

  • ↵1-a Ekins et al., 1997.

  • ↵1-b 100% = 2.8 pmol/mg microsomal protein as determined using CYP2B6 expressed in microsomes from B-lymphoblastoid cells as the standard.