Table 3

Kinetic parameters for the efflux of [3H]TC and [3H]BQ-123 from the brain after microinjection

InhibitorTCABQ-123
Substrate(nmol/0.2 μl injectate)
[3H]TC K m = 0.396IC50 = 0.116
[3H]BQ-123IC50= 0.0740 K m = 2.92
  • Kinetic parameters for the efflux of [3H]TC and [3H]BQ-123 are summarized. Experimental data shown in figs.2, 3 and 5 were analyzed kinetically to obtain kinetic parameters.