Table 2

STS pharmacokinetics2-a

DosePre-bolus (p)End-bolus (p)15 min, post (p)15 min, post (u)24 hr post bolusn
pu
 4 g/m2 N/D50.50.313.3517
 8 g/m2 1.5896.850.01453.8N /DN /D3
12 g/m2 160.497.62102.5N /DN /D3
16 g/m2 308.0125.31641.8N /DN /D2
20 g/m2 330.8235.81981.2N /D2.138
  • 2-a Mean values are expressed as milligrams per deciliter. p, plasma; u, urine; N/D, not detectable.