Table 1

Effects of dietary glycine on recovery from early alcoholic liver injury

ParametersGroupsSix Wk EthanolOne Wk RecoveryTwo Wk Recovery
ASTControl161  ± 3391  ± 886.4  ± 6
Glycine146  ± 2469  ± 21-a 64.7  ± 51-a
ALTControl75  ± 934.3  ± 337  ± 4
Glycine70  ± 622.7  ± 11-b 30  ± 4
Scores1-c Control5.5  ± 0.24.5  ± 0.22.5  ± 0.5
Glycine5.6  ± 0.23.1  ± 0.41-a 0.5  ± 0.51-a
SteatosisControl18.5  ± 2.89.8  ± 1.68.4  ± 1.2
Glycine18.2  ± 2.35.6  ± 0.71-a 5.2  ± 1.3
WBC1-d Control3.7  ± 0.22.6  ± 0.11.8  ± 0.1
Glycine3.6  ± 0.32.3  ± 0.11.2  ± 0.21-a
Necrosis1-e Control3.8  ± 0.13.1  ± 0.11.6  ± 0.1
Glycine3.9  ± 0.12.2  ± 0.11-b 1.3  ± 0.1
  • 1-a P < .05 compared to the control group.

  • 1-b P < .01 compared to the control group.

  • 1-c Represents pathology scores.

  • 1-d Represents numbers of infiltrating leukocytes/100 hepatocytes.

  • 1-e Represents numbers of necrotic cells/hepatocytes.