Table 3

Estimates of the pEC50 values and maximal inhibitory effects of oxotremorine-M inhibition on isoproterenol- and forskolin-stimulated cAMP accumulation

ConditionOxotremorine-M
pEC50 ± S.E.M.3-aEmax3-b
Isoproterenol (0.1 μM)8.00  ± 0.2248.9%
Forskolin (4 μM)7.77  ± 0.1381.7%
  • 3-a Calculated as the average and S.E.M. of the pEC50s from each individual experiment.

  • 3-b Maximal effect is the percent inhibition of stimulated cAMP after subtraction of basal.