Table 2

Best inhibitor blocking model for three coexpressed subunit pairs inXenopus oocytes

InhibitorKv1.1/Kv1.2Kv1.2/Kv1.4Kv1.1/Kv1.4
δ-DTXSingle subunitN.S.2-b Single subunit
DTX-ISingle subunit2-a Single subunitN.D.2-c
Tityustoxin-KαSingle subunitNot single subunitN.S.
TEAEnergy additivityN.S.N.D.

  • ↵2-a Determined with a DTX-I-insensitive mutant Kv1.1 subunit [Hopkins et al., 1994b].

  • ↵2-b N.S. indicates that neither subunit is inhibitor-sensitive.

  • ↵2-c N.D. not determined.