Table 1

Initial clearance Cli (in 10−3 ml/min/106) and hepatic extraction Ecalc andEin vivo for rocuronium and digoxin

CliEcalcEin vivo
Rocuronium1.290.210.41
Digoxin
 50 nM2.400.33
 2.5 nM1.120.180.13