Effect of i.t. administration of AMPA (LY215490) and NMDA (MK-801) glutamate antagonists on the latency (ms) of potentials in the PAG evoked by PLN stimulation
| Before | After | ||||
|---|---|---|---|---|---|
| 0.1 μg | 1 μg | 10 μg | 30 μg | ||
| LY215490 (n = 5) | 35.2 ± 4.8 | 35.8 ± 4.7 | 36.2 ± 5.2 | 35.8 ± 5.6 | 36.9 ± 5.6 |
| Before | After | ||||
|---|---|---|---|---|---|
| 1 μg | 10 μg | 30 μg | 100 μg | ||
| MK-801 (n = 5) | 39.0 ± 4.7 | 41.0 ± 4.1 | 41.5 ± 3.7 | 41.1 ± 3.4 | 41.6 ± 3.6 |
| Before | After | ||
|---|---|---|---|
| MK-801 (1 μg) and LY215490 (0.1 μg) (n = 5) | 38.0 ± 2.5 | 38.1 ± 2.1 | |