Table 3

Ki values for anandamide, CP 55,940 and SR 141716A

Brain RegionAnandamideKi (nM)CP-55,940 Ki(nM)SR 141716A Ki (nM)
Entorhinal cortex9563-a 10.23-a 36  ± 4
Parietal cortex713  ± 76.7  ± 2.135  ± 14
Occipital cortex328  ± 8617.5  ± 7.834  ± 7
Frontal cortex661  ± 1458.5  ± 0.226  ± 10
Medial caudate-putamen566  ± 939.0  ± 2.031  ± 8
Lateral caudate-putamen515  ± 685.3  ± 1.352  ± 17
Dentate gyrus400  ± 728.5  ± 0.736  ± 53-b
CA1438  ± 876.0  ± 0.924  ± 33-b
CA3489  ± 1767.4  ± 1.338  ± 53-b
Substantia nigra512  ± 1697.3  ± 2.995  ± 293-b
Molecular layer of the cerebellum861  ± 3212.5  ± 4114  ± 193-b

  • Results are presented as means ± S.E. for three experiments unless indicated otherwise.

  • ↵3-a N = 2.

  • ↵3-b N = 6.