Table 4

Pearson correlations between binding affinity at the various transporters and receptors^4-a

	Correlation Coefficient (r)	P value	n
rat SERT × hSERT [³H]citalopram	0.964	<.0001	19
hSERT [³H]5-HT × hSERT [³H]citalopram	0.962	<.0011	18
hSERT [³H]5-HT × rat SERT	0.961	<.0001	18
Rat NET × hNET [³H]nisoxetine	0.980	<.0001	19
hNET [³H]NE × hNET [³H]nisoxetine	0.982	<.0001	19
hNET [³H]NE × rat NET	0.957	<.0001	19
Muscarinic × rat SERT	0.618	.043	11
hSERT [³H]citalopram	0.704	.016	11
hSERT [³H]5-HT	0.701	.016	11
rat NET	0.806	.003	11
hNET [³H]nisoxetine	0.820	.002	11
hNET [³H]NE	0.751	.008	11
5-HT_2A × 5-HT_1A	0.847	.001	11
H₁	0.842	.001	11
alpha-1	0.865	<.001	11
alpha-2	0.868	<.001	11
5-HT_1A × 5-HT_2A	0.847	.001	11
H₁	0.639	.034	11
alpha-1	0.803	.003	11
alpha-2	0.933	<.001	11
H₁× 5-HT_2A	0.842	.001	11
5-HT_1A	0.639	.034	11
alpha-1	0.739	.009	11
alpha-2	0.613	.046	11
Alpha-1 × 5-HT_2A	0.865	<.001	11
5-HT_1A	0.803	.003	11
H₁	0.739	.009	11
alpha-2	0.920	<.001	11
Alpha-2 × 5-HT_2A	0.868	<.001	11
5-HT_1A	0.933	<.001	11
H₁	0.613	.046	11
alpha-1	0.920	<.001	11

↵4-a Only those correlations that were significant are shown.