Table 1

Total cumulative increase in wakefulness (minutes)1-a

nMeanS.E.Duration
MOD 3001-b 10108.77.8First 4 h post-treatment
Vehicle2010.63.7
METH 1.01-b 9116.010.4
Vehicle2012.94.3
MOD 1001267.65.6First 3 h post-treatment
Vehicle2014.03.2
METH 0.51080.97.1
Vehicle2016.43.4
MOD 301-b 933.95.0First 2 h post-treatment
Vehicle2016.72.8
ANOVAFP
MAIN EFFECT, dF = (9,149)62.990.0001
Planned contrasts
 MOD 3001-b-Vehicle190.630.0001
 METH 1.0-Vehicle195.740.0001
 METH 1.01-b-MOD 3000.74N.S.
 MOD 100-Vehicle63.930.0001
 METH 0.5-Vehicle82.280.0001
 METH 0.5-MOD 1002.860.0929  N.S.
 MOD 30-Vehicle5.440.0211
  • 1-a Total increase in minutes of wakefulness post-treatment over the corresponding base line period 24 h earlier. MOD, modafinil; METH, methamphetamine.

  • 1-b Values of MOD and METH are stated in milligrams per kilogram i.p.