Table 2

Scatchard analysis of [³H]cocaine binding in hair

Sex and Ethnicity	Hair Color	K_d₁ (nM)	Hill Coef.^2-a	B_max₁^2-b(pmol/mg)	K_d₂ (nM)	Hill Coef.^2-a	B_max₂^2-b (pmol/mg)
Male Mongoloid	Dark	22 ± 1	0.97–0.99	1.2 ± 0.2	1102 ± 145	0.95–0.99	34.8 ± 1.9
Male Africoid	Dark	112 ± 23	0.96–0.98	1.7 ± 0.4	1566 ± 326	0.98–1.0	18.0 ± 0.9
Female Africoid	Dark	82 ± 5	0.95–0.99	0.5 ± 0.1	4433 ± 400	0.96–0.99	9.5 ± 1.0
Male Caucasoid	Light	6 ± 1	0.96–1.00	0.04 ± 0.01	906 ± 169	0.97–0.99	1.9 ± 0.2

Data are expressed as mean ± S.E.M. Each specimen was analyzed three times in duplicate using EBDA and Ligand programs to obtain binding parameters. Binding parameters for one light female Caucasoid specimen could not be determined because specific binding was not consistently detected.

↵2-a Range for Hill coefficients.
↵2-b B _max₁ andB _max₂ indicate the density of high- and low-affinity binding sites, respectively.