The biodisposition of radioactive AN and its metabolites in mice over a 30-min time course
| Time (min) | ng ExogenousAN/μl or mg wetwt. ± S.E.M. | ||
|---|---|---|---|
| Brain | Adrenal | Heart | |
| 1 | 25.12 ± 3.91 | 237.54 ± 40.11 | 99.67 ± 40.81 |
| 5 | 23.44 ± 2.34 | 52.95 ± 7.95* | 35.39 ± 4.36* |
| 15 | 17.08 ± 2.13 | 42.28 ± 9.62* | 19.77 ± 0.93* |
| 30 | 23.42 ± 3.91 | 148.61 ± 49.41* | 23.32 ± 4.58* |
| Kidney | Liver | Lung | |
| 1 | 122.98 ± 17.24 | 58.64 ± 15.19 | 139.33 ± 13.32 |
| 5 | 72.64 ± 6.95* | 63.31 ± 10.53 | 33.54 ± 8.71* |
| 15 | 83.75 ± 7.56* | 105.41 ± 9.36 | 32.73 ± 4.39* |
| 30 | 107.51 ± 11.04 | 161.29 ± 26.79* † | 34.55 ± 5.08* |
| Diaphragm | Fat | Plasma | |
| 1 | 54.69 ± 6.21 | 3.62 ± 0.71 | 112.86 ± 32.24 |
| 5 | 100.79 ± 52.45 | 2.34 ± 1.14 | 15.42 ± 1.88* |
| 15 | 21.41 ± 3.55* | 5.36 ± 1.47 | 16.53 ± 4.34* |
| 30 | 19.8 ± 1.24* | 8.8 ± 3.37 | 56.75 ± 10.15* |
Values are x̄ ± S.E.M., n = 6.
* P < .05 vs. 1 min,† P < .05 vs. 5 min.