Table 1

Effect of pretreatment with Ro 25-1392 on the number and affinity of VIPR1 and VIPR2

TreatmentVIPR1VIPR2
KdBmaxKdBmax
nM 106receptors/cell nM 106 receptors/cell
Control4.6  ± 1.00.8  ± 0.113  ± 1.01.2  ± 0.2
Ro 25-1392 (0.1 μM)3.8  ± 0.80.8  ± 0.112  ± 2.70.5  ± 0.1*

Each value is the mean plus or minus S.E.M. of the results of four experiments.

  • * P < .05.