Table 1

Percentage of unmetabolized [3H]AZT and [3H]DDI in the ipsilateral cerebrum and carotid vein

Sample1-anIntact Percentage1-b
%
Ipsilateral cerebrum
 [3H]AZT495.9  ± 1.0
 [3H]DDI390.4  ± 1.6
Ipsilateral carotid vein plasma
 [3H]AZT4103  ± 0.8
 [3H]DDI389.0  ± 4.9
  • 1-a Samples were collected 15 min after the intracerebral microinjection of [3H]AZT or [3H]DDI.

  • 1-b Each value represents the mean ± S.E.