Table 5

Case histories, P450 2E1 contents and the MAOS activity of human hepatic microsomes5-a

PatientSexAgeDiseaseAlcoholTobaccoP450 2E1MAOS Activity
1M60HCC8016.010.44
2M59HCC3022.310.59
3M66HCC23.060.96
4M55HCC202.170.19
5M69HCC108.540.41
6M50HCC206.990.32
7M65HCC605.610.30
8M45HCC1218.630.58
9M44HCC7.130.32
10F28AD34.571.32
  • 5-a Alcohol consumption is expressed as grams of ethanol per day. Smoking habits are expressed as cigarettes per day. P450 2E1 contents are expressed as picomoles per milligram of protein. MAOS activity is expressed as nanomoles of product per minute per milligram of protein. HCC, hepatocellular carcinoma; AD, accidental death.