(B) Concentration of selexipag and its metabolite ACT-333679 in the plasma after oral administration of selexipag at 30 mg/kg.
| Lung Selexipag and Metabolite (ng/g) | ||
|---|---|---|
| 30 mg/kg selexipag (twice daily) | 30 mg/kg selexipag metabolite (ACT-333679) (twice daily) | |
| Average | 7.02 | 270.63 |
| S.E.M. | 2.05 | 71.17 |
| n | 9 | 9 |