Agonist effects of somatostatin-14 and octreotide for inhibition of forskolin-stimulated cAMP accumulation in CHO-K1 cells expressing rat, monkey, and human recombinant sst2 receptors
Data are mean EC50 values (95% confidence interval) from 3–4 experiments expressed as nmol/l.
| Compound | Rat (n = 3) | Monkey (n = 4) | Human (n = 3) |
|---|---|---|---|
| Somatostatin-14 | 0.15 (0.12–0.17) | 0.11 (0.082–0.14) | 0.24 (0.19–0.30) |
| Octreotide | 0.030 (0.026–0.034) | 0.037 (0.030–0.047) | 0.030 (0.026–0.035) |