TABLE 1

Comparison of the glomerular capillary pressure in FHH 1BN (WT) and FHH 1BN Add3 KO rats treated with L-NAME and an HS diet vs. time-control groups

TreatmentStrainn of Ratsn of PSF MeasuredPSF (mm Hg)π (mm Hg)PGC (mm Hg)
Time controlWT64329.8 ± 2.220.350.1 ± 2.2
Add3 KO64030.9 ± 3.820.3 ± 1.751.2 ± 4.3
L-NAME + HSWT43035.7 ± 5.1*20.6 ± 0.556.2 ± 4.9*
Add3 KO42645.5 ± 2.9 *18.9 ± 1.264.3 ± 2.7 *
  • Mean ± S.D. (if available). Statistical analysis was performed using Student’s unpaired t test. PGC, glomerular capillary pressure; π, systemic oncotic pressure.

  • P < 0.05 vs. corresponding values in WT rats.

  • * P < 0.05 vs. the control values within the strain.