TABLE 2

Comparison of EC50 values for TAS1R2/R3 agonists from experiments using different concentrations of sucrose as the training cue and control standard

Experiment 2AExperiment 2BExperiment 2C
REB A56 µM (44–73 µM)60 µM (53–69 µM)30 µM (26–34 µM)
SCRL79 µM (64–99 µM)132 µM (96–178 µM)98 µM (90–107 µM)
ACE K310 µM (251–380 µM)381 µM (329–441 µM)153 µM (125–187 µM)
SUC40 mM (31–52 mM)51 mM (45–59 mM)31 mM (28–34 mM)
  • Sucrose training cue and control standard for Experiment 2A = 100 mM; for Experiment 2B = 300 mM; for Experiment 2C = 30 mM. Values are given as EC50 values derived from nonlinear regression of the concentration-response data for discrimination of rebaudioside A (REB A), sucralose (SCRL), acesulfame potassium (ACE K), and sucrose (SUC). Values in parentheses represent 95% CIs.