TABLE 1

High-resolution liquid chromatography-tandem mass spectrometry analysis of proteins that increase or decrease ≥1.5-fold after treatment with SF-3-030 or SCH772984 for 4 h relative to untreated A375 cells (set at 1)

Protein changes common to both SF-3-030 and SCH772984 are italicized.

Proteins that increase with SF-3-030Fold increase
 ZNF77416.28
 MEMO110.55
 TTC39C5.18
 MYO18A4.18
 TCF42.24
 HMOX11.77
Proteins that decrease with SF-3-030Fold decrease
 HCCS3.35
 KIAA12112.24
 ACTN21.66
AHCY1.53
Proteins that increase with SCH772984Fold increase
 TMTC15.15
 SRGAP11.47
Proteins that decrease with SCH772984Fold decrease
 TTC292.44
AHCY1.48
  • ACTN2, α-actinin-2; KIAA1211, Capping protein inhibiting regulator of actin dynamics; MYO18A, unconventional myosin-XVIIIa; SRGAP1, SLIT-ROBO Rho GTPase-activating protein 1; (TMTC1), transmembrane and TPR repeat-containing protein 1; TTC29, tetratricopeptide repeat protein 29; TTC39C, Tetratricopeptide repeat protein 39C