TABLE 4

Recovery of administered [14C]-veverimer in excreta and carcasses of male and female Wistar Han rats

Sample% of Administered Dose
Males (n = 3)Females (n = 3)
MeanS.D.MeanS.D.
Total feces97.091.7295.054.38
Total urine0.020.010.020.01
Total expired aira0.020.010.010.01
Cage washbNDNCNDNC
CarcassbNDNCNDNC
Total recovery97.131.7295.084.38
  • NC, not calculable; ND, radioactivity not detectable.

  • a Up to 72 h postdose, as this time sampling was discontinued as per plan because of radioactivity not being detectable in the 24−48 and 48−72-h collections.

  • b At 168 h postdose only.