Enhanced effect of sialorphin on the inhibitory potency of ME in MVD in the presence of ACP
| ACP (M each) | Sia (M) | IC50 (×10−10 M) | Ratio of Potency |
|---|---|---|---|
| None | None | 177.56 ± 25.07 | 1 |
| 5 × 10−6 | None | 6.60 ± 0.31 | 27.27 ± 4.39 |
| 5 × 10−6 | 10−4 | 4.09 ± 0.46 | 45.20 ± 8.87* |
| 5 × 10−6 | 2 × 10−4 | 4.12 ± 0.55 | 44.88 ± 8.28** |
Sia, sialorphin.
Dunn’s post hoc test compared with ME alone, *P < 0.05; **P < 0.01, n = 4.