TABLE 3

IR + CHBP + CASP3siRNA vs. IR + CHBP, top five upregulated and downregulated genes

The genes in italic were discussed for their potential function in IR-induced AKI. P < 0.05.

Accession NumberGene SymbolGene NameFold Change
Upregulated
NM_001001450SSXB2Synovial sarcoma, X member B, breakpoint 214.730
NR_0281114930523C07RIKRIKEN cDNA 4930523C07 gene10.131
NM_011414SLPISecretory leukocyte peptidase inhibitor8.478
NM_009253SERPINA3MSerine (or cysteine) peptidase inhibitor, clade A, member 3M8.289
NM_175309UPK3BUroplakin 3B5.483
Downregulated
AK0161054930553I04RIKRIKEN cDNA 4930553I04 gene−8.735
NM_0297472410137M14RIKRIKEN cDNA 2410137M14 gene−5.134
NM_147025OLFR380Olfactory receptor 380−4.354
NM_134160MCOLN3Mucolipin 3−4.142
NM_001163513DLG5Discs large MAGUK scaffold protein 5−3.700