Tissue-to-plasma ratio for Δ9-THC and its metabolites (11-OH-THC and 11-COOH-THC) in brain or WAT from adolescent and adult mice after intraperitoneal injection of Δ9-THC (5 mg/kg)
| Analyte | Dose Δ9-THC | Brain:Plasma | WAT:Plasma | ||
|---|---|---|---|---|---|
| Adult | Adolescent | Adult | Adolescent | ||
| Δ9-THC | 5 mg/kg | 1.9 | 0.8* | 200.9 | 242.5 |
| 11-OH-THC | 6.3 | 3.8* | 29.7 | 19.6* | |
| 11-COOH-THC | 0.4 | 0.2** | 0.4 | 0.2*** | |
↵* P < 0.5; **P < 0.01; ***P < 0.001. Student’s t test, n = 4 animals per data point.