Treatment | Saline | Morphine Sulfate (MS) | An2-M6G | An2-morphine | |||
---|---|---|---|---|---|---|---|
n | 10 | 10 | 10 | 10 | 10 | 10 | 10 |
Dose (mg/kg) | 1 | 5 | 10 | 4 | 20 | 20 | |
Equimolar MS | 1 | 5 | 5.5 | ||||
Progression of the charcoal meal in the intestine (% ± S.E.M.) | 73.4 ± 2.2 | 58 ± 2.7* | 49.7 ± 2.7*** | 28.6 ± 3.7**** | 61.5 ± 3.3 | 59.7 ± 3.1$ | 45.1 ± 5.1**** |
MS, morphine sulfate.
↵* P < 0.05, ***P < 0.001, and ****P < 0.0001 compared with saline group; $P < 0.05 An2-M6G (20 mg/kg) compared with An2-morphine (20 mg/kg); Kruskal-Wallis nonparametric test followed by Dunn’s multiple comparison test.