Mean (S.E.M.) functional potency (IC50, nM) of ubrogepant for cloned CGRP receptors in HEK293 cellsa
| Cloned Human CGRP Receptor | Cloned Rhesus CGRP Receptor | ||
|---|---|---|---|
| No Serum | + 50% Human Serum | No Serum | + 50% Rhesus Serum |
| 0.081 ± 0.005 | 0.19 ± 0.01 | 0.07 ± 0.02 | 0.30 ± 0.01 |
IC50, half-maximal inhibitory concentration.
↵a n = 3–21.