TABLE 4

Serum biochemistry analytes

Analytes were assessed across treatment groups by one-way ANOVA followed by Tukey’s post hoc analysis. Significant differences in pairwise comparisons among groups for individual analytes are demonstrated using superscript letters. Values are the mean ± S.D.

TestCKM i.p. MC (n = 6)CKM i.p. SAL (n = 5)Sham i.p. MC (n = 5)Sham i.p. SAL (n = 4)CKM PO MC (n = 3)Sham PO MC (n = 5)Sham PO SAL (n = 5)
Glucose (mg/dl)274.5 ± 44.5282.0 ± 49.6319.2 ± 108.2268.0 ± 53.5281.0 ± 48.7357.0 ± 77.7269.6 ± 55.5
Blood urea nitrogen (mg/dl)25.2 ± 1.8a21.6 ± 3.326.0 ± 3.5b22.5 ± 3.322.7 ± 3.819.4 ± 2.1a,b22.2 ± 2.6
Calcium (mg/dl)10.8 ± 0.910.9 ± 0.611.4 ± 0.510.7 ± 0.310.3 ± 0.411.3 ± 0.710.4 ± 0.4
Phosphate (mg/dl)14.7 ± 1.914.3 ± 1.413.9 ± 1.114.2 ± 0.312.8 ± 2.214.6 ± 1.813.3 ± 0.7
Total protein (g/dl)6.1 ± 0.56.1 ± 0.55.8 ± 0.45.9 ± 0.35.7 ± 0.25.8 ± 0.25.5 ± 0.3
Albumin (g/dl)3.5 ± 0.23.5 ± 0.23.2 ± 0.23.3 ± 0.13.5 ± 0.33.5 ± 0.23.5 ± 0.2
Globulin (g/dl)2.6 ± 0.3c2.6 ± 0.32.6 ± 0.2d2.6 ± 0.3e2.2 ± 0.12.3 ± 0.12.0 ± 0.2c,d,e
Total bilirubin (mg/dl)0.2 ± 0.10.2 ± 0.10.1 ± 0.00.2 ± 0.10.2 ± 0.10.2 ± 0.10.1 ± 0.1
Alkaline phosphatase (U/l)125.5 ± 43.3178.4 ± 57.9f83.6 ± 26.4f,b157.0 ± 41.0132.0 ± 25.2189.8 ± 65.4b152.6 ± 24.5
Alanine aminotransferase (U/l)54.7 ± 25.855.6 ± 24.443.8 ± 10.140.8 ± 11.846.0 ± 12.837.6 ± 13.137.0 ± 7.3
Aspartate aminotransferase (U/l)251.2 ± 335.9100.4 ± 36.762.6 ± 19.885.0 ± 31.870.0 ± 14.070.2 ± 40.489.4 ± 66.2
Cholesterol (mg/dl)142.2 ± 40.8148.0 ± 26.1142.0 ± 18.5149.0 ± 17.4133.3 ± 16.0165.8 ± 18.5138.2 ± 27.3
  • a CKM MC i.p. vs. sham MC PO.

  • b Sham MC i.p. vs. sham MC PO.

  • c CKM MC i.p. vs. sham SAL PO.

  • d Sham MC i.p. vs. sham SAL PO.

  • e CKM MC PO vs. sham SAL PO.

  • f CKM SAL i.p. vs. sham MC i.p.