TABLE 1

Physical characteristics of polyplex formulated at different siRNA-to-polymer (N/P w/w) ratios

siRNA/P(SiDAAr)5P3 (N/P)Mean Hydrodynamic DiameterPolydispersity IndexZeta Potential
nmmV
1/2326.80.21+8.7
1/3294.70.64+26.2
1/4349.50.34+30.0
1/5230.60.52+42.5
1/6240.10.46+36.3