Component/Evaluation Parameter | Formulation | |||
---|---|---|---|---|
FN 2 | FNG 1 | FNG 2 | FNG 3 | |
Molar ratio (Phospholipid 90H:Span60) | 1:1 | 1:1 | 1:1 | 1:1 |
Phospholipid 90H (mg) | 122 | 122 | 122 | 122 |
Span 60 (mg) | 36 | 36 | 36 | 36 |
TPGS (mg) | 10 | 10 | 10 | 10 |
GG (mg) | — | 10 | 20 | 30 |
Viscosity (cP) (formulation) | 16.8 ± 3.1 | 18.7 ± 1.5 | 27.5 ± 1.4 | 39.6 ± 2.6 |
GFT (s) | — | <5 | <5 | <5 |
GRT (h) | — | <1 | 3 to 4 | 6 to 7 |
Viscosity (cP) (Hydrogel) | — | 94.1 ± 2.5 | 206.9 ± 4.1 | 651.3 ± 1.7 |
Work of adhesion (g. s) | — | 0.56 ± 0.05 | 0.94 ± 0.02 | 1.33 ± 0.04 |
—, indicates not tested.
g. s, gram. sec.