TABLE 7

Estimated relative effects of CNP treatment on growth of body, tail, tibia, and ulna (relative increase in growth compared with vehicle treatment [% (95% confidence interval) in monkeys]

TransCon CNP 40 µg CNP/kg Per WeekTransCon CNP 100 µg CNP/kg Per WeekDaily CNP-39 Molecule 20 µg CNP/kg Per Day
Body1.0 (−2.3; 4.4)4.8 (1.1; 8.5)*3.3 (0.0; 6.6)*
Tail1.4 (−2.7; 5.5)8.6 (3.7; 13.4)*2.8 (−1.3; 6.9)
Tibia1.7 (−2.0; 5.4)6.0 (2.1; 9.9)*2.9 (−1.0; 6.8)
Ulna0.9 (−2.8; 4.7)2.7 (−1.1; 6.5)0.8 (−2.9; 4.5)