Probes and custom conjugates used to optimize and perform PK studies
| Probe | Molecular Mass | Description | Excitation/Emission | Applications |
|---|---|---|---|---|
| kDa | nm | |||
| FRS680 | 1.6 | Folate-based NIR fluorescent imaging probe | 670/690 | Oncology and inflammation |
| AS680 | 70 | NIR fluorescent-labeled PEG-polylysine copolymer used as a vascular imaging probe | 670/690 | Vascularity and vascular leak changes in oncology and inflammation |
| AS750 | 70 | NIR fluorescent-labeled PEG-polylysine copolymer used as a vascular imaging probe | 750/770 | Vascularity and vascular leak changes in oncology and inflammation |
| IS750 | 1.28 | NIR fluorescent-labeled small molecule αVβ3 integrin antagonist | 755/775 | Oncology, atherosclerosis, angiogenesis |
| GFR680 | ∼6.0 | NIR fluorescent-labeled inulin | 670/690 | Measuring GFR by blood PK |
| IgG1-VT680XL | 150 | Normal mouse IgG1 labeled with VivoTag 680XL | 665/688 | Control |
PEG, polyethylene glycol.