TABLE 6

Cardiovascular parameters in ranolazine or best standard therapy (BST) arms from T1 to T5

Data are medians with interquartile ranges and were analyzed by two-tailed Mann-Whitney test (for comparisons between arms) or two-tailed Wilcoxon signed rank test for comparisons within arms.

ParametersRanolazine 
(n = 12)BST (n = 12)P Value
LVEF (%)
 T160 (56–61)60 (59–62)0.610
 T560 (58–65)60 (58–64)0.837
 P (T1 vs. T5)0.3240.572
SBP (mm Hg)
 T1120 (110–130)120 (113–120)0.845
 T5120 (111–129)110 (110–115)0.051
 P (T1 vs. T5)0.8870.046
DBP (mm Hg)
 T178 (70–80)80 (70–85)0.613
 T578 (70–80)70 (70–79)0.364
 P (T1 vs. T5)0.6650.160
QTc (mm Hg)
 T1423 (405–430)405 (390–420)0.220
 T5419 (400–430)417 (410–439)0.772
 P (T1 vs T5)0.6890.220
BMI (kg/m2)
 T121 (19–26)25 (20–27)0.338
 T522 (20–26)25 (20–28)0.400
 P (T1 vs T5)0.1020.824