In vitro plasma protein binding ratios of SCO-267 in rats, dogs, and humans
The mean of three samples is presented. Matrices shown are pooled plasma samples of 20 male Sprague-Dawley rats (8 weeks old), pooled plasma samples of 10 male beagles (10 months old), and pooled plasma samples of 10 male and 10 female humans.
| Matrix | Concentration of Compounds | Binding Ratio |
|---|---|---|
| μg/ml | % | |
| Rat | 0.05 | 99.6 |
| 0.5 | 99.6 | |
| 5 | 99.6 | |
| Dog | 0.05 | 99.6 |
| 0.5 | 99.7 | |
| 5 | 99.7 | |
| Human | 0.05 | 99.7 |
| 0.5 | 99.7 | |
| 5 | 99.7 |