The permeability-surface area product (PS) and cerebrovascular plasma volume (Vp) of 125I-ApoA-I in various regions of rat brain at 60 minutes
Data represent mean ± S.D. (n = 6). 131I-ApoA-I was injected to serve as a measure of Vp. According to one-way ANOVA followed by Bonferroni post tests, the PS and Vp values for the brain stem and cerebellum are significantly greater (P < 0.05) than that of other regions.
| Brain Region | PS | Vp |
|---|---|---|
| ml/g per second × 10−6 | µl/g | |
| Cortex | 0.39 ± 0.08 | 6.93 ± 0.59 |
| Caudate putamen | 0.28 ± 0.07 | 6.49 ± 0.93 |
| Hippocampus | 0.28 ± 0.07 | 6.94 ± 0.84 |
| Thalamus | 0.36 ± 0.12 | 9.45 ± 1.27 |
| Brain stem | 0.69 ± 0.22 | 14.37 ± 2.50 |
| Cerebellum | 0.76 ± 0.21 | 17.18 ± 3.38 |