TABLE 1

Observational scale used to score convulsion intensity

Intensity ScoreDescriptionExample
0Typical mouse behaviorEmbedded Image
1Rigidity, leg splay, full body twitchesEmbedded Image
2Rigidity, leg splay, full body twitches, and handling-elicited convulsionEmbedded Image
3Rigidity, leg splay, full body twitches, and spontaneous convulsionEmbedded Image