TABLE 1

 Doxycycline levels in cortex (CTX), hippocampus (HIPP), cerebellum (CB), striatum (STR), and in the “rest of the brain” (ROB) of WT and APP23 mice 24 hours after the last of four daily intraperitoneal injections (mean ± S.D. of three mice; two females and one male per group)

Two-way analysis of variance indicated no significant overall difference between WT and APP23 mice and multiple comparison test indicated no significant differences for the single brain areas.