TABLE 2

Dysregulated molecules that may contribute to the pathogenesis of ME/CFS

Dysregulated Molecules that May Contribute to ME/CFS Pathogenesis
Cachexins
Calcineurin
Heavy metals
Herbicides
Inflammatory cytokines
Leptin
Melatonin
MicroRNAs
Mitochondrial enzymes
Neuroendocrine disruptors
Neuropeptides
Neurotransmitters
Reactive oxygen species
Toxins (mycotoxins, Borrelia toxins)
Uncoupling protein 2
Xenobiotics