TABLE 3

Ca2+ mobilization potencies for ligands at various primate OTRs

Data are presented as means ± log S.E.M.

OTR (n = 3)Ca2+ EC50
Pro8-OTLeu8-OTAVP
nM
Human0.072 ± 0.120.127 ± 0.100.864 ± 0.07a,b
Macaque1.341 ± 0.112.025 ± 0.117.981 ± 0.12a,b
Marmoset0.115 ± 0.150.176 ± 0.140.459 ± 0.14b
Titi monkey0.595 ± 0.091.010 ± 0.094.821 ± 0.09a,b

  • ↵a Indicates a significant within-species difference compared with Leu8-OT using a Bonferroni-corrected cutoff of P < 0.0167.

  • ↵b Indicates a significant within-species difference compared with Pro8-OT using a Bonferroni-corrected cutoff of P < 0.0167.