Intronic SNPs associated with NAPQI-induced hepatotoxicity [Moyer et al. (2011), n = 176]

SNPGeneNameAllelesaMAFCategoryP Valueb
rs1532815LMX1ALIM homeobox transcription factor 1 alphaA/T0.33Intron6.04E−7
rs3795578ETNK2Ethanolamine kinase 2C/T0.40Intron7.18E−6
rs3825924ALDH1A3Aldehyde dehydrogenase 1 family member A3C/T0.21Intron1.73E−5
rs1343151IL23RInterleukin 23 receptorG/A0.34Intron1.91E−5
rs17640676KCNJ3Potassium voltage-gated channel subfamily J member 3G/T0.23Intron2.09E−5
rs4869233MCTP1Multiple C2 and transmembrane domain containing 1T/C0.32Intron2.28E−5
rs16851554SPAG16Sperm associated antigen 16T/G0.15Intron2.46E−5
rs3208829LAMA4Laminin subunit alpha 4C/G0.16Intron2.54E−5
rs11153350RFPL4BRet finger protein like 4BG/A0.15Intron2.54E−5
rs3746923UBASH3AUbiquitin associated and SH3 domain containing AC/T0.43Intron2.56E−5
  • a Major allele/minor allele.

  • b The top-10 intronic SNPs based upon P value are presented.