TABLE 2

Sensitivity of SW-480 and SW-620 human colon cancer cells to compound 16

Data are the mean ± S.E.M. of at least three independent experiments, each performed in triplicate.

Colorectal Cancer Cell Line	IC₅₀ (µM)^{^a}	GI₅₀ (µM)^{^b}	TGI (µM)^{^c}	LC₅₀ (µM)^{^d}
SW-480	4.03 ± 0.183	2.67 ± 0.27	24.31 ± 15.32	84 ± 17
SW-620	0.83 ± 0.083	0.57 ± 0.067	14.47 ± 12.77	75 ± 25

↵^a Effective concentration, or compound concentration required for 50% inhibition of cell proliferation, after 48-hour treatment.
↵^b Compound concentration required for 50% cell growth inhibition, after 48-hour treatment.
↵^c Compound concentration required for total cell growth inhibition, after 48-hour treatment.
↵^d Compound concentration required for 50% cell death, after 48-hour treatment.