TABLE 4

Pharmacokinetic parameters after single oral administration of TAS-303 at 1, 3, or 10 mg/kg in normal female rats

Results are shown as the mean ± S.E.M.

DoseTmaxCmax
hnM
1 mg/kg0.75 ± 0.2911.7 ± 5.0
3 mg/kg0.75 ± 0.2949.1 ± 13.9
10 mg/kg1.25 ± 0.50453.0 ± 28.8
  • Tmax, time to peak concentration.