Effect of LABAs on CRE-dependent reporter activation in BEAS-2B cells
Parameters were derived from the data in Fig. 1. β2A was used as a reference agonist and assigned a value of 1.
| Treatment | N | p[A]50 | Emax (fold) | α |
|---|---|---|---|---|
| β2A | 7 | 8.70 ± 0.04 | 33.3 ± 1.9 | 1 |
| Formoterol | 7 | 10.43 ± 0.06 | 31.8 ± 3.5 | 0.96 |
| Indacaterol | 7 | 8.84 ± 0.08 | 31.9 ± 5.6 | 0.96 |
| Salmeterol | 7 | 9.11 ± 0.10 | 33.0 ± 4.0 | 0.99 |
| Picumeterol | 8 | 9.72 ± 0.07 | 31.3 ± 3.4 | 0.94 |