TABLE 2

Model parameter estimates corresponding to all the tumor cell lines analyzed

The model parameters are defined in Materials and Methods.

Tumor Line	Cell Line	Parameter
		λ₀	λ₁	TV₀	TV_th	IAV λ₀	IAV λ₁	IAV TV₀	RUV
		day⁻¹	mm³/day	mm³	mm³	CV%	CV%	CV%	Log mm³
Lung	A549	0.051	58.5	48.2	1150	19.8^{^a}		29.5^{^a}	0.205
Lung	H460	0.104	237	71.3	2280	25.2		25.9	0.148
Lung	HCC827	0.100	35.1	21.8	351	16.9			0.194
Lung	Calu-6	0.0875	126	49.9	1440	27.2	53.2	12.6	0.147
Lung	DMS53	0.0438	27.6	16.0	630	11.0			0.316
Lung	H1650	0.0575	48.0	50.6	835	20.1		12.8	0.201
Lung	H1975	0.104	188	46.3	1810	14.8			0.202
Lung	H358	0.0204	115	88.6	5640	30.0			0.129
Lung	H441	0.0342	75.0	69.6	2190	68.6		40.1	0.223
Lung	H2122	0.103	42.6	60.2	414	20.4	45.1	23.0	0.151
Renal	ACHN	0.0249	12.8	123	514	68.7	42.5	19.7	0.162
Renal	CAKI-1	0.0265	64.2	102	2420			14.3	0.239
Renal	786-o	0.0489	29.5	82.4	603	22.4	67.7	26.4	0.176
Melanoma	A2058	0.129	55.9	64.7	433	8.20	39.6		0.154
Melanoma	A375	0.0948	101	69.3	1070	39.8	67.2	36.3	0.193
Melanoma	GAK	0.0277	19.0	88.8	686	45.5		17.6	0.191
Melanoma	SK-MEL-30	0.0640	84.8	148	1330	45.9		23.7	0.200
Lymphoma	JEKO-1	0.0825	217	62.9	2630	10.5		19.3	0.284
Lymphoma	OCI-LY-19	0.138	464	30.0	3360	9.70			0.320
Lymphoma	WILL-2	0.203	352	25.3	1730			28.0	0.263
Colon	COLO205	0.106	31.9	65.6	301	25.1	88.1	61.5	0.211
Colon	HCT116	0.121	176	67.5	1460	19.3			0.409
Glioblastoma	U-87-MG	0.0547	51.9	80.4	949	38.9		29.0	0.400
Leukemia	MV411	0.0695	66.5	44.3	957	25.4^{^b}	72.6^{^b}	34.7	0.194
Ovarian	A2780	0.103	254	59.0	3660	23.8			0.216
Ovarian	SKVO-3	0.0798	55.4	61.4	694	10.0			0.203
Breast	MB231	0.500 FIX	2.58	81.9	5.00		41.8	23.6	0.122
Pancreas	MIA PaCa-2	0.120	21.6	43.1	180		58.2	15.4	0.114

RUV, residual unexplained variability.
↵^a Correlation between IAV λ₀ and IAV TV₀ of −90%.
↵^b Correlation between IAV λ₀ and IAV λ₁ of 100%.