TABLE 2

Summary of in vitro K_i values for displacement of ³H-NMS binding from human recombinant M1–M5 mAChRs

K_i values for LSN3172176, xanomeline, and GSK1034702 were derived from IC₅₀ values, as described in Materials and Methods, from the data shown in Fig. 3. Values in parentheses indicate the fold-selectivity vs. the M1 mAChR.